Rebecca Corrigan

Sir Henry Dale Research Fellow – Department of Microbiology and Biotechnology

Dr Rebecca Corrigan first became enthralled by science at school and specialised in microbiology from the mid-point of her undergraduate studies. After a very successful summer placement, which produced 2 papers, she was certain that a career in scientific research was for her. She ended her PhD with a further 4 1st author papers that helped her secure a postdoc position but, as a naturally shy person, she had to push herself to speak at conferences and international events. She went on to produce more high impact publications during her postdoc and was able to focus on her enjoyment of bench science, including a funded trip to the US to learn a new technique to bring back to the lab. After one failed attempt, she consulted her supervisor for invaluable help and advice on applying for fellowships, which led to her securing her current 5-year role.

Click here for full staff profile, including research interests, teaching commitments, and publications list.

Have courage, get the confidence to talk to your PI about applying for a fellowship and work out where the lines are and where your research - where your autonomy - will begin.

Career Timeline

2004

BA (Mod. Hons) Microbiology, Trinity College Dublin, Ireland

2004–2008

Demonstrating microbiological laboratory techniques to undergraduate students

2005

Other author paper

Wright JS, Traber KE, Corrigan R, Benson SA, Musser JM & Novick RP (2005) The agr Radiation: an Early Event in the Evolution of Staphylococci. Journal of Bacteriology, 187(16), 5585-5594.

2007

Speaker at the Gordon Research Conference on Staphylococcal Diseases, Les Diablerets, Switzerland

2007

First author paper

Corrigan RM, Rigby D, Handley P & Foster TJ (2007) The role of Staphylococcus aureus surface protein SasG in adherence and biofilm formation. Microbiology, 153(8), 2435-2446.

2007–2008

Wellcome Trust Advanced Source Instructor, Sanger Institute

2008

PhD, Microbiology. Trinity College Dublin, Ireland

September 2008–December 2014

Postdoctoral research associate, Imperial College London, UK

2008

Other author paper

Traber KE, Lee E, Benson S, Corrigan R, Cantera M, Shopsin B & Novick RP (2008) agr function in clinical Staphylococcus aureus isolates. Microbiology, 154(8), 2265-2274.

2008–2013

Mentoring PhD students

2009

First author paper

Corrigan RM, Miajlovic H & Foster TJ (2009) Surface proteins that promote adherence of Staphylococcus aureus to human desquamated nasal epithelial cells. BMC Microbiology, 9(1), 22-22.

2009

First author paper

Corrigan RM & Foster TJ (2009) An improved tetracycline-inducible expression vector for Staphylococcus aureus. Plasmid, 61(2), 126-129.

2010

Referee for Biomedical Engineering Online

2010

Joint first author paper

Geoghegan JA, Corrigan RM, Gruszka DT, Speziale P, O’Gara JP, Potts JR & Foster TJ (2010) Role of Surface Protein SasG in Biofilm Formation by Staphylococcus aureus. Journal of Bacteriology, 192(21), 5663-5673.

2011–2013

Referee for Acta Biomaterialia

2011

Second author paper

Xia G, Corrigan RM, Winstel V, Goerke C, Grundling A & Peschel A (2011) Wall Teichoic Acid-Dependent Adsorption of Staphylococcal Siphovirus and Myovirus. Journal of Bacteriology, 193(15), 4006-4009.

2011

Speaker at the Gordon Research conference on Staphylococcal Diseases, Italy

2011

Second author paper

Wörmann ME, Corrigan RM, Simpson PJ, Matthews SJ & Gründling A (2011) Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes. Molecular Microbiology, 79(3), 566-583.

2011

First author paper

Corrigan RM, Abbott JC, Burhenne H, Kaever V & Gründling A (2011) c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress. PLoS Pathogens, 7(9), e1002217-e1002217.

2012

EMBO Short-Term Fellowship (€6,542.40) – Dr Vincent Lee’s lab, University of Maryland, USA

2012

Second author paper

Smith EJ, Corrigan RM, van der Sluis T, Gründling A, Speziale P, Geoghegan JA & Foster TJ (2012) The immune evasion protein Sbi of Staphylococcus aureus occurs both extracellularly and anchored to the cell envelope by binding lipoteichoic acid. Molecular Microbiology, 83(4), 789-804.

2013

Prize for best speaker at 2013 Staphylococcal GBI conference, Dublin, Ireland

2013

First author paper

Corrigan RM & Gründling A (2013) Cyclic di-AMP: another second messenger enters the fray. Nature Reviews Microbiology, 11(8), 513-524.

2013

First author paper

Corrigan RM, Campeotto I, Jeganathan T, Roelofs KG, Lee VT & Grundling A (2013) Systematic identification of conserved bacterial c-di-AMP receptor proteins. Proceedings of the National Academy of Sciences, 110(22), 9084-9089.

2014

Referee for Molecular Microbiology

2014

Speaker at the Young Microbiology Symposium, Dundee, Scotland

2014

Other author paper

Reichmann NT, Piçarra Cassona C, Monteiro JM, Bottomley AL, Corrigan RM, Foster SJ, Pinho MG & Gründling A (2014) Differential localization of LTA synthesis proteins and their interaction with the cell division machinery in Staphylococcus aureus. Molecular Microbiology, 92(2), 273-286.

2015

Sir Henry Dale Research Fellow, Department of Molecular Biology and Biotechnology, University of Sheffield, UK

2015

Referee for the journal Microbiology

2015

Level 3 module (Microbial Structure and Dynamics: Genes and Populations

2015

Invited seminar at the Krebs Institute Symposium, University of Sheffield, UK

2015

First author paper

Corrigan RM, Bowman L, Willis AR, Kaever V & Gründling A (2015) Cross-talk between Two Nucleotide-signaling Pathways in Staphylococcus aureus. Journal of Biological Chemistry, 290(9), 5826-5839.

2015–present

PhD supervisor

2016

First author paper

Corrigan R, Bellows LE, Wood A & Grundling A (2016) ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria. Proceedings of the National Academy of Sciences of the United States of America.

2016

Referee for Scientific Reports

2016

Other author paper

Schuster CF, Bellows LE, Tosi T, Campeotto I, Corrigan RM, Freemont P & Grundling A (2016) The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC in Staphylococcus aureus. Science Signaling, 9(441).